RO5192022
RO5192022 is a TAAR1 agonist and a radioligand for TAAR1 binding assays. RO5192022 exhibits antipsychotic-like properties. RO5192022 can be used in studies related to schizophrenia.
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- CAS. Nr.: 1043489-40-2
- Formel: C9H8F2N2O
- Molecular Weight:198.17
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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TAAR1 |
TAAR1 is a trace amine-sensing GPCR enriched in the central nervous system. It regulates dopamine and serotonin monoamine neural circuits, and serves as a therapeutic target for schizophrenia, depression and drug addiction.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1043489-40-2
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Molecular Weight 198.17
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Formel C9H8F2N2O
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SMILES
NC1=N[C@H](CO1)C2=CC=C(C=C2F)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Revel FG, et al.. TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proceedings of the National Academy of Sciences of the United States of America. 2011 May 17;108(20):8485-90. [Content Brief]
[2]. Aleksandrov AA, et al.. The TAAR5 agonist α-NETA causes dyskinesia in mice. Neuroscience letters. 2019 Jun 21;704:208-211. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
RO5192022 Related Classifications
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