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Art. -Nr.: HY-N19135

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SB87-H

SB87-H is a Pestalone-type benzophenone compound that exists in the endophytic fungus Pestalotiopsis trachicarpicola SC-J551 and the lichen endophytic fungus Pestalotiopsis rhododendri LF-19-12. SB87-H exhibits cytotoxicity against cancer cells and epithelial cells, and possesses antibacterial activity against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, and vancomycin-sensitive Enterococcus faecium. SB87-H can be used in studies related to bacteria infections.

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CAS. Nr.: 163768-82-9
Formel: C₂₀H₂₀O₆
Molecular Weight:356.37

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

SB87-H Chemical Structure

CAS. Nr.: 163768-82-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

In Vitro

SB87-H (compound 9) (0.31-10 μg/mL; 6-8 h) inhibits the growth of Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, and vancomycin-susceptible Enterococcus faecium with an MIC of 10 μg/mL, and shows no activity against vancomycin-resistant Enterococcus faecium^[1].
SB87-H (0.016-50 μM) potently induces cytotoxicity in A549, HeLa, HepG2, MCF-7, and Vero cells with IC₅₀ values ranging from 1.5-2.2 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 163768-82-9
Molecular Weight 356.37
Formel C₂₀H₂₀O₆
SMILES

O=CC1=C(C=C(C(C/C=C(C)\C)=C1C(C2=C(C=C(C)C=C2O)O)=O)O)O
Structure Classification
- Phenols
- Polyphenols
Initial Source
- Microorganisms
Pestalotiopsis trachicarpicola SC-J551
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Jiang Z, et al. Pestalotinones A-D, new benzophenone antibiotics from endophytic fungus Pestalotiopsis trachicarpicola SC-J551. The Journal of antibiotics. 2022 Apr;75(4):207-212. [Content Brief]

[2]. Song F. Antimicrobial Natural Products. Antibiotics. 2022 Dec 7;11(12):1765.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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