2438 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2438)

2438 Results for "decrease" in MCE Product Catalog:

Art. -Nr.: HY-113797
CAS. Nr.: 62435-92-1
Target:  

Adrenergic Receptor

Forschungsgebiete:  

Others

RS-52367 is a potent syntex β-adrenergic antagonist. RS-52367 decreases intraocular pressure with a mild systemic effect in dogs .
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Art. -Nr.: HY-116169
CAS. Nr.: 255734-04-4
Target:  

Adrenergic Receptor

Forschungsgebiete:  

Metabolic Disease Endocrinology

KUC-7322, a selective β3 -adrenoceptor agonist, is the active form of ritobegron. Ritobegron decreases intravesical pressure with minimal effects on the cardiovascular system.
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Art. -Nr.: HY-120240
CAS. Nr.: 1380201-88-6
Target:  

Others

Forschungsgebiete:  

Others

AND-302 is a small molecule anticonvulsant with activity in preventing glutamate- or hydrogen peroxide-induced cell death and decreased neuronal viability in in vitro hippocampal cultures.
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Art. -Nr.: HY-W516943
CAS. Nr.: 700-07-2
CI-624 decrease secretion volumes and outputs of hydrogen, sodium and potassium ions and of pepsin. CI-624 can be used in the research of cancer and autoimmune diseases .
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Art. -Nr.: HY-116960
CAS. Nr.: 113243-75-7
FR 76830 is a bradycardic agent with cardiomyocyte protective effects. FR 76830 attenuates the decrease in myocardial pH during the early stage of ischemia. FR 76830 improves ATP levels during the late stage of ischemia. FR 76830 reduces heart rate in a dose-dependent manner without decreasing the rate-pressure product of the myocardium. FR 76830 exerts cardioprotective effects during ischemia and reperfusion. FR 76830 can be used for the research of myocardial ischemia-reperfusion injury .
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Art. -Nr.: HY-120459
CAS. Nr.: 110230-95-0
Target:  

Na+/K+ ATPase

Forschungsgebiete:  

Others

Rs-029 is an inhibitor Na+/K+ ATPase and an activator for Mg2+ ATPase. Rs-029 decreases the ATP level in red blood cells .
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Art. -Nr.: HY-W130132
CAS. Nr.: 21193-80-6
Bromotubercidin is a RNA synthesis inhibitor. Bromotubercidin induces biphasic decreases in vasopressin biosynthesis and causes progressive reduction in vasopressin biosynthesis .
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Art. -Nr.: HY-167674
CAS. Nr.: 109453-73-8
Target:  

Endogenous Metabolite

Forschungsgebiete:  

Neurological Disease

Bmapn has rewarding and reinforcing properties, decreases dopamine transporter and increases dopamine receptor D2 gene expression in the striatum .
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Art. -Nr.: HY-W280622
CAS. Nr.: 93963-24-7
Target:  

Drug Derivative

Forschungsgebiete:  

Neurological Disease

N-Ethyl-4-methoxyamphetamine hydrochloride is an analog of 4-Methoxyamphetamine. The addition of an N-ethyl substituent decreases analgesic potency.
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Art. -Nr.: HY-115304
CAS. Nr.: 101374-18-9
Target:  

Melatonin Receptor

Forschungsgebiete:  

Neurological Disease

UCM 793 is a non-selective MT1/MT2 receptor agonist (pKis: 9.09 (MT1 receptor); 9.19 (MT2 receptor)). UCM793 increases the number of episodes and decreases the length of the episodes of wakefulness. UCM 793 influences quality of the vigilance states. UCM 793 decreases sleep onset without having an effect on NREM sleep maintenance .
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Art. -Nr.: HY-P4182
CAS. Nr.: 121801-61-4
Target:  

Inhibitory Antibodies

Forschungsgebiete:  

Neurological Disease

Schistoflrfamide, a FMRFamide-related peptide, is an inhibitory neuropeptide. Schistoflrfamide decreases the amplitude and frequency of myogenic contractions and reduce basal tension visceral muscle .
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Art. -Nr.: HY-104037R
CAS. Nr.: 2055536-64-4
Synonyms: LYC-55716 (Standard)
Target:  

Reference Standards ROR

Forschungsgebiete:  

Cancer

Cintirorgon (Standard) is the analytical standard of Cintirorgon (HY-104037). This product is intended for research and analytical applications. Cintirorgon (LYC-55716) is a first-in-class, selective and orally bioavailable RORγ agonist. Cintirorgon (LYC-55716) modulates gene expression of RORγ expressing T lymphocyte immune cells, resulting in enhanced effector function, as well as decreased immunosuppression, resulting in decreased tumor growth, and improved survival .
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Art. -Nr.: HY-N15229
CAS. Nr.: 2259327-01-8
Resinacein L is an inhibitor for α-glucosidase with an IC50 of 0.635 mM. Resinacein L slows down the digestion and absorption of carbohydrates, thereby decreasing postprandial blood glucose .
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Art. -Nr.: HY-106329
CAS. Nr.: 119804-96-5
Target:  

Others

Forschungsgebiete:  

Cancer

DMDC is an anti-tumor agent. DMDC induces chemotherapy-induced myelosuppression, characterized by decreases in leukocyte and neutrophil counts. DMDC can be used for the study of advanced malignancies .
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Art. -Nr.: HY-133098
CAS. Nr.: 1021950-14-0
Juncutol is a potent inducible nitric oxide synthase (iNOS) inhibitor. Juncutol decreases the LPS (HY-D1056)-stimulated iNOS protein expression .
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Art. -Nr.: HY-136346
CAS. Nr.: 163217-74-1
Target:  

Drug Metabolite

Forschungsgebiete:  

Cardiovascular Disease

2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids .
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Art. -Nr.: HY-137391
CAS. Nr.: 15833-07-5
Target:  

Estrogen Receptor/ERR

Forschungsgebiete:  

Metabolic Disease

2-Bromoestradiol is a estrogen 2-hydroxylase inhibitor. 2-Bromoestradiol decreases irreversible binding of radiolabeled estradiol metabolite(s) to microsomal proteins .
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Art. -Nr.: HY-168365
CAS. Nr.: 26126-01-2
Target:  

Drug Isomer

Forschungsgebiete:  

Neurological Disease

(±)-Pellotine hydrochloride (Compound 2) is an alkaloid, which is found in L. diffusa and L. fricii. (±)-Pellotine hydrochloride decreases locomotor activity and the amount of rapid eye movement (REM) sleep in mice .
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Art. -Nr.: HY-169960
Target:  

mTOR

Forschungsgebiete:  

Cancer

2DII is a potent and selective mTORC2 inhibitor. 2DII selectively binds mSin1 PH domain and decreases the expression of AKT1 phosphorylation .
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Art. -Nr.: HY-173466
CAS. Nr.: 2922530-99-0
LT-188A is a potent TGR5 agonist with an EC50 of 23 μM. LT-188A decreases the levels of inflammatory mediators in macrophages .
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