18 Results for "

Hydroxycotinine

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "Hydroxycotinine" in MCE Product Catalog:

Art. -Nr.: HY-113239
CAS. Nr.: 34834-67-8
Reinheit:  99.00%
Hydroxycotinine is a nicotine metabolite commonly found in the urine of smokers. Hydroxycotinine is the primary biomarker of tobacco/nicotine vapor exposure, formed from the conversion of nicotine via cotinine. Hydroxycotinine serum levels in rodents are influenced by sex and co-exposure to nicotine vapor and ethanol. Hydroxycotinine elevation is associated with decreased eGFR and increased risk of chronic kidney disease. Hydroxycotinine can be used in research related to chronic kidney disease .
loading...
    loading...
17
17 Publications Verification
Art. -Nr.: HY-17365
CAS. Nr.: 79517-01-4
Synonyms: SMS 201-995 acetate
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
loading...
    loading...
3
3 Cited Publications
Art. -Nr.: HY-B1178
CAS. Nr.: 486-56-6
Synonyms: (-)-Cotinine; (S)-Cotinine; NIH-10498
Cotinine ((-)-Cotinine) is an orally active alkaloid found in tobacco and is the primary metabolite of nicotine. Cotinine is metabolized by CYP2A13 into trans-3'-hydroxycotinine. Cotinine is used as a biomarker to measure exposure to tobacco smoke components. Cotinine has vasodepressor activity. The mixture of cotinine and nicotine (Nicotine) has antiproliferative activity against pterygium. (S)-(-)-Cotinine activates nicotinic acetylcholine receptors (nAChR) in a calcium-dependent manner, leading to the release of dopamine (Dopamine, HY-B0451). Cotinine ((-)-Cotinine) is used in research related to cardiovascular and inflammatory diseases .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-105055
CAS. Nr.: 77327-05-0
Reinheit:  99.95%
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
loading...
    loading...
Art. -Nr.: HY-125586
CAS. Nr.: 21150-22-1
Reinheit:  ≥96.0%
Forschungsgebiete:  

Cancer

β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
loading...
    loading...
Art. -Nr.: HY-P10447
CAS. Nr.: 103651-09-8
Synonyms: Fengycin IX; SNA-60-367-3
Target:  

Phospholipase Fungal

Forschungsgebiete:  

Infection

Plipastatin A1 (Fengycin IX; SNA-60-367-3) is a lipopeptide with phospholipase A2 inhibitory activity. Plipastatin A1 inhibits conidial germination of Botrytis cinerea in vitro and reduces the incidence of gray mold on tomato leaves. Plipastatin A1 is applicable to research related to gray mold [1][2].
loading...
    loading...
Art. -Nr.: HY-P4755
CAS. Nr.: 282726-24-3
Forschungsgebiete:  

Others

N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a polypeptide composed of L-phenyleline and L-leucine bound to aniline groups. N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide can be used to quantitatively determine the N-terminal heme adduct formed upon exposure to propylene oxide (PO) .
loading...
    loading...
Art. -Nr.: HY-P3100
CAS. Nr.: 939960-34-6
Target:  

Parasite

Forschungsgebiete:  

Infection

Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC50 value of 34.5 μg/mL .
loading...
    loading...
Art. -Nr.: HY-125357
CAS. Nr.: 148619-41-4
Target:  

Inhibitory Antibodies

Forschungsgebiete:  

Metabolic Disease

Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC50 of 0.027 μM in 3T3-L1 adipocytes .
loading...
    loading...
Art. -Nr.: HY-113239S
CAS. Nr.: 1311275-10-1
Hydroxycotinine-d3 is the d3-labeled Hydroxycotinine (HY-113239). Hydroxycotinine is a nicotine metabolite commonly found in the urine of smokers. Hydroxycotinine is the primary biomarker of tobacco/nicotine vapor exposure, formed from the conversion of nicotine via cotinine. Hydroxycotinine serum levels in rodents are influenced by sex and co-exposure to nicotine vapor and ethanol. Hydroxycotinine elevation is associated with decreased eGFR and increased risk of chronic kidney disease. Hydroxycotinine can be used in research related to chronic kidney disease .
loading...
    loading...
Art. -Nr.: HY-113239S1
CAS. Nr.: 159956-78-2
rel-Hydroxycotinine-d3 is the d3-labeled Hydroxycotinine (HY-113239). Hydroxycotinine is a nicotine metabolite commonly found in the urine of smokers. Hydroxycotinine is the primary biomarker of tobacco/nicotine vapor exposure, formed from the conversion of nicotine via cotinine. Hydroxycotinine serum levels in rodents are influenced by sex and co-exposure to nicotine vapor and ethanol. Hydroxycotinine elevation is associated with decreased eGFR and increased risk of chronic kidney disease. Hydroxycotinine can be used in research related to chronic kidney disease .
loading...
    loading...
Art. -Nr.: HY-154772S
trans-3’-Hydroxycotinine-O-β-glucuronide-d3 is deuterated labeled trans-3’-Hydroxycotinine-O-β-glucuronide.
loading...
    loading...
Art. -Nr.: HY-158104
Target:  

ATF6

Forschungsgebiete:  

Others

LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .
loading...
    loading...
Art. -Nr.: HY-160251
CAS. Nr.: 132929-88-5
Synonyms: (3'R,5k'S)-trans-3'-Hydroxycotinine glucuronide
Target:  

Drug Metabolite

Forschungsgebiete:  

Others

3-HC-Gluc ((3’R,5k’s)-trans-3’ -Hydroxycotinine glucuronide) The trans-structure of 3-HC, the main metabolite of nicotine .
loading...
    loading...
Art. -Nr.: HY-113239S2
CAS. Nr.: 2714435-80-8
(Rac)-Hydroxycotinine-d3 is deuterated labeled Hydroxycotinine (HY-113239). Hydroxycotinine is the main nicotine metabolite detected in smokers urine.
loading...
    loading...
Art. -Nr.: HY-P11783
CAS. Nr.: 86711-55-9
Target:  

Fungal

Forschungsgebiete:  

Infection

Surfactin C2 is a lipopeptide produced by Bacillus subtilis A18 with antifungal activity. Surfactin C2 acts against Heterobasidion annosum and Heterobasidion parviporum. Surfactin C2 exerts its activity mainly through membrane‑active effects to disrupt fungal cell structures and inhibit mycelial growth. Surfactin C2 can be used for the research of butt rot and root rot of conifers .
loading...
    loading...
Art. -Nr.: HY-P2209
CAS. Nr.: 53947-96-9
Synonyms: Daechuine S27; N-Demethylamphibine H
Nummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC50 of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca 2+-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis .
loading...
    loading...
Art. -Nr.: HY-P4948
CAS. Nr.: 1926163-49-6
Forschungsgebiete:  

Others

Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .
loading...
    loading...
  • 1