TTX-P
TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C46H35N4O5PS
- Molecular Weight:786.83
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
TTX-P (10 μM) is responsive to alkaline phosphatase (ALP) and correspondingly emits NIR-II fluorescent signals which are suitable for imaging (at 920 nm)[1].
TTX-P (10 μM; HepG2, 4T1, and LO2 cells) can detect and monitor the activity of ALP in cancer cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:BALB/C nude mice with 4T1 cells xenografts (female, 4-5 weeks old)[1]
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Dosage:5 mg/kg
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Administration:Intratumoral injection
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Result:Enhanced NIR-II fluorescence signals in a time-dependent manner.
Chemical Information
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Molecular Weight 786.83
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Formel C46H35N4O5PS
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SMILES
CC1=CC=C(C=C1)N(C2=CC=C(C=C2)C3=N/C(S/C3=C\C4=C5OC6=C(C=C5CCC4)C=CC(C7=CC=C(C=C7)OP(O)(O)=O)=C6)=C(C#N)/C#N)C8=CC=C(C=C8)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
TTX-P Related Classifications
HY-149835 Related Classifications
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