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Art. -Nr.: HY-P10878

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UK140

UK140 is the inhibitor for urokinase-type plasminogen activator (uPA) with K_i of 0.20 µM and 2.79 µM for huPA anf muPA. UK140 can be used in metastasis-related research.

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Formel: C₇₂H₁₀₅N₁₉O₂₅S₃
Molecular Weight:1732.91

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

UK140 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
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- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
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Calculators
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Classifications
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Biologische Aktivität

Beschreibung

UK140 is the inhibitor for urokinase-type plasminogen activator (uPA) with K_i of 0.20 µM and 2.79 µM for huPA anf muPA. UK140 can be used in metastasis-related research^[1].

IC₅₀ & Target

K_i: 0.20 µM (huPA); 2.79 µM (muPA)

Chemical Information

Molecular Weight 1732.91

Formel C₇₂H₁₀₅N₁₉O₂₅S₃

Sequence

Ala-Cys-Asn-Ser-Lys-Phe-Ser-Gly-Cys-Gly-Val-Asp-Pro-Ser-Ser-Cys-Gly (cyclized via TBMB and Cys2,9,16)

Sequence Shortening

ACNSKFSGCGVDPSSCG (cyclized via TBMB and Cys2,9,16)

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)

COA (2659 KB)

Elemental Analysis Report (2659 KB)

HNMR (2659 KB)

CNMR (2659 KB)

RP-HPLC (2659 KB)

NP-HPLC (2659 KB)

MS (2659 KB)

LCMS (2659 KB)

IR (2659 KB)

GC (2659 KB)

OR (2659 KB)

SDS-PAGE (2659 KB)

SEC-HPLC (2659 KB)

Other Report (2659 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Mazzocato Y, et al., A novel genetically-encoded bicyclic peptide inhibitor of human urokinase-type plasminogen activator with better cross-reactivity toward the murine orthologue. Bioorg Med Chem. 2023 Nov 15;95:117499. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

=
Konzentration Konzentration

×
Volumen Volumen

×
Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

×

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

=

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

×

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

UK140 Related Classifications

HY-P10878 Related Classifications

Metabolic Enzyme/Protease

PAI-1

Disease Areas

Cancer

Peptides

Peptide and Derivatives

Inhibitors and Substrates

Cancer

Cancer Targeted Therapy Cancer Metabolism and Metastasis

Bioz

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Keywords

UK140
UK 140
UK-140
PAI-1
Inhibitor
inhibitor
inhibit

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UK140

Biologische Aktivität

Beschreibung

IC50 & Target

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

UK140 Related Classifications

HY-P10878 Related Classifications

Bioz

Keywords

Your Recently Viewed Products

IC₅₀ & Target