VHC-7
VHC-7 is a potent and selective adenylyl cyclase type 8 (AC8) agonist, with an EC50 value of 105.2 nM. VHC-7 increases cyclic adenosine monophosphate (cAMP) levels. VHC-7 can be used for the study of central nervous system disorders and heart diseases.
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- CAS. Nr.: 14750-21-1
- Formel: C18H15Cl2NO3
- Molecular Weight:364.22
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
0.1052 μM
Compound: VHC-7
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Agonist activity at recombinant human AC8 expressed in human HEK293 cells assessed as fold increase in cAMP level by LANCE Ultra cAMP Detection kit method
Agonist activity at recombinant human AC8 expressed in human HEK293 cells assessed as fold increase in cAMP level by LANCE Ultra cAMP Detection kit method
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[PMID: 31776060] |
Chemical Information
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CAS. Nr. 14750-21-1
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Molecular Weight 364.22
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Formel C18H15Cl2NO3
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SMILES
O=C(C1(CC2=CC=C(Cl)C=C2Cl)C(NC3=C1C=CC=C3)=O)OCC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
VHC-7 Related Classifications
HY-130629 Related Classifications
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