YH16899
Based on 1 Customer Validation
YH16899 binds Lysyl-tRNA synthetase (KRS), and inhibits membrane translocation of KRS. YH16899 impares the interaction of KRS with 67LR. YH16899 inhibits tumor metastasis in mouse models.
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- Reinheit: 99.63%
- CAS. Nr.: 1428623-14-6
- Formel: C19H13F5N2O3S
- Molecular Weight:444.38
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Speicherung:
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NCI-H226 | EC50 |
8.5 μM
Compound: YH16899
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Antimigratory activity against human NCI-H226 cells assessed as inhibition of cell migration measured after 12 hrs by Transwell assay
Antimigratory activity against human NCI-H226 cells assessed as inhibition of cell migration measured after 12 hrs by Transwell assay
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[PMID: 33831781] |
Chemical Information
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CAS. Nr. 1428623-14-6
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Appearance Solid
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Molecular Weight 444.38
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Formel C19H13F5N2O3S
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Color White to off-white
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SMILES
O=C(C1=CC=CC(C(F)(F)F)=C1)/N=C2N(C(CC)C(O)=O)C3=CC(F)=C(F)C=C3S/2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
YH16899 Related Classifications
HY-15782 Related Classifications
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