COH1
Based on 1 Customer Validation
COH1 is a ribonucleotide reductase (RR) inhibitor. COH1 can be used in research into cancer, mitochondrial diseases, and neurodegenerative diseases.
For research use only. We do not sell to patients.
- Purity: 99.25%
- CAS No.: 20217-22-5
- Formula: C11H10N2O3S
- Molecular Weight:250.27
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
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Biological Activity
COH1 binds to RRM2 and interfers with the activity of the RRM1/RRM2 enzyme complex, thereby inhibiting the RR activity and reducing the dNTP pool, thus affecting cell cycle and proliferation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 20217-22-5
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Appearance Solid
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Molecular Weight 250.27
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Formula C11H10N2O3S
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Color White to off-white
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SMILES
O=C(C)NC1=NC(C2=CC(O)=C(O)C=C2)=CS1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COH1 Related Classifications
HY-149439 Related Classifications
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