EthD-d5 bromide
EthD-d5 bromide is the deuterium labeled Ethidium bromide. EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
For research use only. We do not sell to patients.
- CAS No.: 1579939-34-6
- Formula: C21H15D5BrN3
- Molecular Weight:399.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1579939-34-6
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Unlabeled Cas 1239-45-8
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Molecular Weight 399.34
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Formula C21H15D5BrN3
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SMILES
[2H]C([2H])([2H])C([2H])([2H])[N+]1=C(C=C(C=C2)N)C2=C(C=CC(N)=C3)C3=C1C4=CC=CC=C4.[Br-]
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Synonyms
EtBr-d5; Homidium-d5 bromide
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. P Stevenson, et al. Comparison of isometamidium chloride and homidium bromide as prophylactic drugs for trypanosomiasis in cattle at Nguruman, Kenya. Acta Trop. 1995 May;59(2):77-84. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)