PPA
Based on 1 Customer Validation
PPA is an ADC linker (US20060073528A1). PPA can be used for making antibody-drug conjugate.
For research use only. We do not sell to patients.
- Purity: 99.01%
- CAS No.: 452072-22-9
- Formula: C10H13NO2S2
- Molecular Weight:243.35
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Disulfide Cleavable Linker |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 452072-22-9
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Appearance Solid
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Molecular Weight 243.35
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Formula C10H13NO2S2
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Color Light yellow to yellow
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SMILES
CC(SSC1=NC=CC=C1)CCC(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (410.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1093 mL | 20.5463 mL | 41.0926 mL | 102.7314 mL |
| 5 mM | 0.8219 mL | 4.1093 mL | 8.2185 mL | 20.5463 mL | |
| 10 mM | 0.4109 mL | 2.0546 mL | 4.1093 mL | 10.2731 mL | |
| 15 mM | 0.2740 mL | 1.3698 mL | 2.7395 mL | 6.8488 mL | |
| 20 mM | 0.2055 mL | 1.0273 mL | 2.0546 mL | 5.1366 mL | |
| 25 mM | 0.1644 mL | 0.8219 mL | 1.6437 mL | 4.1093 mL | |
| 30 mM | 0.1370 mL | 0.6849 mL | 1.3698 mL | 3.4244 mL | |
| 40 mM | 0.1027 mL | 0.5137 mL | 1.0273 mL | 2.5683 mL | |
| 50 mM | 0.0822 mL | 0.4109 mL | 0.8219 mL | 2.0546 mL | |
| 60 mM | 0.0685 mL | 0.3424 mL | 0.6849 mL | 1.7122 mL | |
| 80 mM | 0.0514 mL | 0.2568 mL | 0.5137 mL | 1.2841 mL | |
| 100 mM | 0.0411 mL | 0.2055 mL | 0.4109 mL | 1.0273 mL |
PPA Related Classifications
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