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Cat. No.: HY-B1796

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Thymol iodide

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Thymol iodide is an iodine derivative of thymol, serving as a mild preservative and fungicide. Thymol iodide is commonly used as an iodine source in the intensive culture of rotifers. Thymol iodide effectively enables Brachionus "Cayman" rotifers to reach iodine levels similar to those of copepods, and maintains a high iodine content during storage. After 28 days of intrapleural injection of Thymol iodide, it does not enhance the efficacy of inducing pleurodesis in rabbits, nor does it improve the efficacy of talc slurry pleurodesis.

For research use only. We do not sell to patients.

CAS No.: 552-22-7
Formula: C₂₀H₂₄I₂O₂
Molecular Weight:550.21

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Thymol iodide Chemical Structure

CAS No.: 552-22-7

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Biological Activity

Description

In Vivo

Combined administration of thymol iodide (50 mg; intrapleural injection; single dose) with 200 mg/kg talc slurry does not enhance the efficacy of pleurodesis in rabbit experiments evaluated by pleural effusion volume, gross adhesion score or microscopic fibrosis score; only 30% of the tested rabbits achieve satisfactory pleurodesis efficacy on the 14th and 28th days post-administration^[1].
Thymol iodide (0.3-25.2 g/kg feed; mixed with enrichment feed; 3 h enrichment) can efficiently enrich the iodine content of rotifers to a level comparable to that of copepods via an extremely low proportion of dietary replacement (accounting for 0.36-2.03% of the total diet), and maintains a stable iodine retention rate when stored at room temperature or low temperature for up to 18 h^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

New Zealand white (male)^[1]
Dosage:

50 mg (as part of iodized talc slurry with 200 mg/kg talc)
Administration:

intrapleural injection; single dose
Result:

Recorded mean pleural fluid volume of 2.2 mL at 48 hours post-injection.
Reported mean gross pleurodesis adhesion score of 2.3 and mean microscopic pleural fibrosis score of 2.0 on day 28.
Found 30% of rabbits (3/10) had a good pleurodesis (score 3 or 4) on day 14 and 30% (3/10) on day 28.
Observed no significant differences in pleural fluid characteristics, gross adhesion scores, microscopic inflammation scores, or microscopic fibrosis scores compared to plain talc controls at any time point.

Chemical Information

CAS No. 552-22-7
Appearance Solid
Molecular Weight 550.21
Formula C₂₀H₂₄I₂O₂
Color Light yellow to yellow
SMILES

CC(C1=C(OI)C=C(C)C(C2=CC(C(C)C)=C(OI)C=C2C)=C1)C
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Ethanol : < 1 mg/mL (insoluble)

H₂O : < 0.1 mg/mL (insoluble)

* Thymol iodide is usually formulated as a suspension.

View the Complete Stock Solution Preparation Table

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (537 KB)
- English - EN (537 KB)
- Français - FR (537 KB)
- Deutsch - DE (537 KB)
- Norwegian - NO (537 KB)
- Español - ES (537 KB)
- Swedish - SV (537 KB)
- Italian - IT (537 KB)
- Korean - KR (537 KB)
- Portuguese - PT (537 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xie C, et al. Comparisons of pleurodesis induced by talc with or without thymol iodide in rabbits. Chest. 1998;113(3):795-799. [Content Brief]

[2]. Srivastava A, Hamre K, Stoss J, et al. A study on enrichment of the rotifer Brachionus “Cayman” with iodine from different sources[J]. Aquaculture, 2012, 334: 82-88.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vivo
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References

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Thymol iodide

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