ATB-343
ATB-343 is a derivative of Indomethacin that releases H2S. H2S has cytoprotective and anti-inflammatory effects, inhibiting leukocyte adhesion to vascular endothelium and leukocyte migration to inflammatory sites. ATB-343 can be used to suppress respiratory infections.
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- CAS No.: 1000700-26-4
- Formule: C28H20ClNO4S3
- Masse moléculaire:566.11
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
3294.4 μM
Compound: 15
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Cytotoxicity against human HepG2 cells assessed as reduction in cell survival after 24 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell survival after 24 hrs by MTT assay
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[PMID: 28646655] |
| L02 | IC50 |
337.2 μM
Compound: 15
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Cytotoxicity against human LO2 cells assessed as reduction in cell survival after 24 hrs by MTT assay
Cytotoxicity against human LO2 cells assessed as reduction in cell survival after 24 hrs by MTT assay
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[PMID: 28646655] |
Chemical Information
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CAS No. 1000700-26-4
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Masse moléculaire 566.11
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Formule C28H20ClNO4S3
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SMILES
O=C(CC1=C(C)N(C(C2=CC=C(C=C2)Cl)=O)C3=C1C=C(C=C3)OC)OC4=CC=C(C(SS5)=CC5=S)C=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATB-343 Related Classifications
HY-15033 Related Classifications
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