CSLP37
CSLP37 is a selective RIPK2 inhibitor with an IC50 of 16.3 nM. CSLP37 shows no inhibitory activity against RIPK1 and RIPK3. CSLP37 displays potent suppression of cellular NOD1 and NOD2 responses.
For research use only. We do not sell to patients.
- CAS No.: 2244984-64-1
- Formula: C25H30FN5O3S
- Molecular Weight:499.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
RIPK2 16.3 nM (IC50) |
Chemical Information
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CAS No. 2244984-64-1
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Molecular Weight 499.60
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Formula C25H30FN5O3S
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SMILES
CCCS(=O)(NC1=CC(C2=CC(C3=CC=C(N4CCNCC4)C=C3)=CN=C2N)=CC(F)=C1OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CSLP37 Related Classifications
HY-123924 Related Classifications
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