Auristatin23
Auristatin23, a conjugate of Auristatin F (HY-15583), is a cytotoxin. Auristatin23 exhibit cytotoxic activities towards targeted cells, including abnormal cells such as cancer cells, that are MDR+ .
For research use only. We do not sell to patients.
- CAS No.: 2375388-36-4
- Formula: C49H84N6O10
- Molecular Weight:917.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2058 | IC50 |
1 nM
Compound: 24
|
Cytotoxicity against human A2058 cells assessed as inhibition of cell growth incubated for 96 hrs by CellTiter-Glo luminescent assay
Cytotoxicity against human A2058 cells assessed as inhibition of cell growth incubated for 96 hrs by CellTiter-Glo luminescent assay
|
[PMID: 39068862] |
Chemical Information
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CAS No. 2375388-36-4
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Molecular Weight 917.23
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Formula C49H84N6O10
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SMILES
OC([C@H](CC1=CC=CC=C1)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCCN(C)C(OC(C)(C)C)=O)=O)=O)=O)OC)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)