Autophagy-IN-12
Autophagy-IN-12 is a Autophagy inhibitor. Autophagy-IN-12 exhibits an IC50 value of >33 μM against the protein-protein interactions of ATG5-ATG16L1 and ATG5-TECAIR.
For research use only. We do not sell to patients.
- CAS No.: 2841473-93-4
- Formula: C30H22N2O5
- Molecular Weight:490.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Autophagy-IN-12 (Compound 17e) exhibits an IC50 value of >33 μM for both ATG5-ATG16L1 and ATG5-TECAIR protein-protein interactions[1].
Autophagy-IN-12 (20 μM; 6 h) increases the autophagy rate of COS-7 cells to 38.94%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:COS-7
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Concentration:20 μM
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Incubation Time:6 h
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Result:Resulted in an autophagy incidence of 38.94% in COS-7 cells.
Chemical Information
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CAS No. 2841473-93-4
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Molecular Weight 490.51
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Formula C30H22N2O5
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SMILES
NC(C(C=C1)=CC=C1C2=CC=C(O2)/C=C(C3=O)\C=C(C4=CC=CC=C4)N3CC5=CC=C(C=C5)C(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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