Basivarsen linker
Basivarsen linker is a linker used in HY-177452 Zeleciment basivarsen for coupling a TfR1-binding Fab (HY-P990780 Zeleciment) and an antisense oligonucleotide. Zeleciment basivarsen is an antibody-oligonucleotide conjugate (AOC) designed to target mutant nuclear myotonic dystrophy protein kinase (DMPK) RNA for RHase H-mediated degradation to correct splicing. It is used for the study of myotonic dystrophy type 1 (DM1).
For research use only. We do not sell to patients.
- CAS No.: 2763758-01-4
- Formula: C50H81N11O16
- Molecular Weight:1092.24
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
CAS No. 2763758-01-4
-
Molecular Weight 1092.24
-
Formula C50H81N11O16
-
SMILES
NC(CCOCCOCCOCCOCCNC(OC[C@H]1[C@]2([H])[C@@]1([H])CCC3=C(N(N=N3)CCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC4=CC=C(C=C4)COC(N)=O)=O)=O)=O)CC2)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)