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Cat. No.: HY-P99279A

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Bavituximab (Mouse IgG1)

Bavituximab (Mouse IgG1) is a mouse-derived IgG1 antibody. The human-mouse chimeric Bavituximab localizes to tumor sites by crosslinking exposed PS with two β2GP1 molecules on the cell surface, activates host effector (immune) functions such as antibody-dependent cellular cytotoxicity, and ultimately leads to tumor vascular destruction.

For research use only. We do not sell to patients.

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Bavituximab (Mouse IgG1) Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Bioz

Biological Activity

Description

Format

Product Image

Chemical Information

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Inhibitory Antibodies User Guide (603 KB)

References

[1]. Gerber DE, et al. Tumor-specific targeting by Bavituximab, a phosphatidylserine-targeting monoclonal antibody with vascular targeting and immune modulating properties, in lung cancer xenografts. Am J Nucl Med Mol Imaging. 2015;5(5):493-503. Published 2015 Oct 12. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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