Benzylisatin
Based on 1 Customer Validation
Benzylisatin is a biologically potent derivative of isatin. Benzylisatin is used to prepare many new biologically potent Schiff bases and complexes suitable for medicinal purposes.
For research use only. We do not sell to patients.
- Purity: 99.74%
- CAS No.: 1217-89-6
- Formula: C15H11NO2
- Molecular Weight:237.26
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CHO-K1 | EC50 |
10 nM
Compound: 14a
|
Positive allosteric modulator activity at human muscarinic receptor subtype 1 expressed in CHO-K1 cells by calcium mobilization assay
Positive allosteric modulator activity at human muscarinic receptor subtype 1 expressed in CHO-K1 cells by calcium mobilization assay
|
[PMID: 25435150] |
| UACC-903 | IC50 |
>100 μM
Compound: Cpd 3
|
Antiproliferative activity against human UACC 903 cells measured after 72 hrs by MTS assay
Antiproliferative activity against human UACC 903 cells measured after 72 hrs by MTS assay
|
[PMID: 31887569] |
Chemical Information
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CAS No. 1217-89-6
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Appearance Solid
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Molecular Weight 237.26
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Formula C15H11NO2
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Color Yellow to brown
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SMILES
O=C1N(CC2=CC=CC=C2)C3=C(C=CC=C3)C1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (421.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2148 mL | 21.0739 mL | 42.1479 mL | 105.3696 mL |
| 5 mM | 0.8430 mL | 4.2148 mL | 8.4296 mL | 21.0739 mL | |
| 10 mM | 0.4215 mL | 2.1074 mL | 4.2148 mL | 10.5370 mL | |
| 15 mM | 0.2810 mL | 1.4049 mL | 2.8099 mL | 7.0246 mL | |
| 20 mM | 0.2107 mL | 1.0537 mL | 2.1074 mL | 5.2685 mL | |
| 25 mM | 0.1686 mL | 0.8430 mL | 1.6859 mL | 4.2148 mL | |
| 30 mM | 0.1405 mL | 0.7025 mL | 1.4049 mL | 3.5123 mL | |
| 40 mM | 0.1054 mL | 0.5268 mL | 1.0537 mL | 2.6342 mL | |
| 50 mM | 0.0843 mL | 0.4215 mL | 0.8430 mL | 2.1074 mL | |
| 60 mM | 0.0702 mL | 0.3512 mL | 0.7025 mL | 1.7562 mL | |
| 80 mM | 0.0527 mL | 0.2634 mL | 0.5268 mL | 1.3171 mL | |
| 100 mM | 0.0421 mL | 0.2107 mL | 0.4215 mL | 1.0537 mL |