BIO-1975900
BIO-1975900 is an allosteric Molecular glue targeting Parkin, with an EC50 of 2.9 µM. BIO-1975900 binds to the RING0/pUb interface to enhance pUb-dependent Parkin activation. BIO-1975900 can be used for research on Parkinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 3140889-82-0
- Formula: C31H30N4O2
- Molecular Weight:490.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3140889-82-0
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Molecular Weight 490.60
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Formula C31H30N4O2
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SMILES
CC(N1CC2=C(C3=CC=C(C(N4CCCC5=C4C=CC=C5)=O)C=C3)C=NN2C[C@@H]1CC6=CC=CC=C6)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BIO-1975900 Related Classifications
HY-190194 Related Classifications
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Keywords
- BIO-1975900
- 3140889-82-0
- BIO1975900
- BIO 1975900
- Molecular Glues
- PINK1/Parkin
- PTEN-induced kinase 1/Parkin
- NMR chemical shift changes
- RING0/pUb interface
- TR-FRET activity assays
- allosteric molecular glue
- hydrophobic groove
- pUb lysine pocket
- pUb-dependent parkin activation
- parkin
- parkinson's disease
- rat parkin R0RB:2×pUb
- Inhibitor
- inhibitor
- inhibit