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Cat. No.: HY-187162

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Blepharin

Blepharin is a naturally occurring benzoxazinoid glucoside with antioxidant activity. As a plant storage-type precursor metabolite, Blepharin can be hydrolyzed by glucosidases in laticifers to produce Blepharigenin when plant tissues are damaged. Blepharin shows weak activity in DPPH free radical scavenging assays and exhibits no significant antifeedant activity against Spodoptera littoralis larvae. Blepharin can be used in studies related to antioxidant and other relevant fields.

For research use only. We do not sell to patients.

CAS No.: 27625-86-1
Formula: C₁₄H₁₇NO₈
Molecular Weight:327.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Blepharin Chemical Structure

CAS No.: 27625-86-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

Blepharin (compound 3) exhibits weak DPPH free radical scavenging activity (EC₅₀ = 232.0 mg/mL)^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Blepharin contained in crude extracts of Blepharis edulis seeds induces concentration-dependent relaxation of spontaneous contractions and 80 mM K⁺-induced contractions of rabbit jejunum via non-competitive calcium channel blockade; this crude extract inhibits contractions of rabbit tracheal smooth muscle; and it blocks adrenaline-mediated aggregation of human platelets^[1].
Blepharin (compound 3) exerts no obvious antifeedant or growth-inhibiting effects on newly hatched larvae of Spodoptera littoralis^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 27625-86-1
Molecular Weight 327.29
Formula C₁₄H₁₇NO₈
SMILES

O=C1NC2=CC=CC=C2O[C@@H]1O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Saqib F, et al. Ethnopharmacological studies on antispasmodic, bronchodilator and antiplatelet aggregation activities of Blepharis edulis, Pers. Asian Journal of Natural & Applied Sciences, 2012, 1(1).

[2]. Traxler F, et al. Specialized plant metabolites from indolic and polyphenolic biosynthetic pathways in Wrightia religiosa (Teijsm. & Binn.) Benth. and Wrightia pubescens R. Br. (Apocynaceae). South African Journal of Botany, 2021, 137: 242-248.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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