BMS-690514 (Standard)
BMS-690514 (Standard) is the analytical standard of BMS-690514 (HY-10333). This product is intended for research and analytical applications. BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR; has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 859853-30-8
- Formule: C19H24N6O2
- Masse moléculaire:368.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-10333
BMS-690514EGFR/VEGFR Inhibitor -
HY-50895
GefitinibEGFR Inhibitor -
HY-50896
ErlotinibEGFR Tyrosine Kinase Inhibitor -
HY-12000
AG490EGFR Inhibitor -
HY-13272
DacomitinibErbB Inhibitor -
HY-32721
NeratinibHER2/EGFR Inhibitor -
HY-16558
ButeinEGFR/PDE Inhibitor -
HY-101084
NSC 228155EGFR Activator -
HY-10222
IxabepiloneMicrotubule Inhibitor -
HY-15312
WP1066JAK2/STAT3 Inhibitor -
HY-10260
VandetanibVEGFR2/3 Inhibitor -
HY-13895
WHI-P154EGFR Inhibitor
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 859853-30-8
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Masse moléculaire 368.43
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Formule C19H24N6O2
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SMILES
O[C@@H]1CN(CC[C@H]1N)CC2=C3C(NC4=CC=CC(OC)=C4)=NC=NN3C=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Wong TW, et al. Antitumor and antiangiogenic activities of BMS-690514, an inhibitor of human EGF and VEGF receptor kinase families. Clin Cancer Res. 2011 Jun 15;17(12):4031-41. [Content Brief]
[2]. Marathe P, et al. Preclinical pharmacokinetics and in vitro metabolism of BMS-690514, a potent inhibitor of EGFR and VEGFR2. J Pharm Sci. 2010 Aug;99(8):3579-93. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMS-690514 (Standard) Related Classifications
HY-10333R Related Classifications
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