2. PROTAC
  3. PROTAC Linkers
  4. Boc-Pip-butyn

Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker. Boc-Pip-butyn is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Boc-Pip-butyn Chemical Structure

Boc-Pip-butyn Chemical Structure

CAS No. : 1346153-07-8

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Based on 1 publication(s) in Google Scholar

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Description

Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker[1]. Boc-Pip-butyn is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target[1]

Alkyl/ether

 

Molecular Weight

237.34

Formula

C14H23NO2
CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

O=C(N1CCC(CC1)CCC#C)OC(C)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
References
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Boc-Pip-butyn Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boc-Pip-butyn1346153-07-8PROTAC LinkersInhibitorinhibitorinhibit

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