BTK degrader-2
BTK degrader-2 (Example 2) is a dual-functional BTK molecular glue degrader, which causes the degradation of BTK through the ubiquitin-proteasome pathway. BTK degrader-2 can be used for the study of B-cell-related diseases.
For research use only. We do not sell to patients.
- CAS No.: 2649400-05-3
- Formula: C17H20N4O4
- Molecular Weight:344.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 2649400-05-3
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Molecular Weight 344.37
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Formula C17H20N4O4
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SMILES
O=C(NC(CC1)=O)[C@@H]1NC(C2=NC=C(N3CCC(CC3)C=O)C=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BTK degrader-2 Related Classifications
HY-179562 Related Classifications
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Keywords
- BTK degrader-2
- 2649400-05-3
- BTK degrader2
- BTK degrader 2
- Btk
- Molecular Glues
- Bruton tyrosine kinase
- Bruton's tyrosine kinase (BTK)
- bifunctional compounds
- proteolytic degradation
- ubiquitin-proteasome pathway
- PROTAC
- ibrutinib resistance
- C481S mutation
- B-cell malignancies
- E3 ubiquitin ligase
- cereblon (CRBN)
- Inhibitor
- inhibitor
- inhibit