BTK-IN-34
BTK-IN-34 (compound 9h) is a selective BTK inhibitor. BTK-IN-34 shows antiproliferative activity in RAMOS cells through selective inhibition of pBTK (Tyr223) without affecting Lyn and Syk, upstream proteins in the BCR signaling pathway.
For research use only. We do not sell to patients.
- CAS No.: 3016419-52-3
- Formula: C22H29N3O4S
- Molecular Weight:431.55
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
BTK-IN-34 (compound 9h; 1-50 μM; 24 hours) decreases the pBTK, pERK 1/2 (Thr202/Tyr204), and p-p38 (Thr180/Tyr182) levels in RAMOS cells[1].
BTK-IN-34 (compound 9h) displays selective cytotoxicity against BTK-high RAMOS cells with an IC50 of 2.75 μM.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:RAMOS cells
-
Concentration:1 μM, 10 μM, 50 μM
-
Incubation Time:24 hours
-
Result:Decreased pBTK (Tyr223) levels.
Chemical Information
-
CAS No. 3016419-52-3
-
Molecular Weight 431.55
-
Formula C22H29N3O4S
-
SMILES
O=C1NC2=C(C=C(S(=O)(N3CCN(C(CCCC)=O)CC3)=O)C=C2)/C1=C4CCCC\4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BTK-IN-34 Related Classifications
HY-162257 Related Classifications
Powered by Bioz