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Cat. No.: HY-150898

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BTK ligand 3

BTK ligand 3 is a BTK ligand that can be used for the synthesis of PROTACs, such as PROTAC BTK Degrader-5 (HY-155072).

For research use only. We do not sell to patients.

CAS No.: 2192282-58-7
Formula: C₂₅H₂₄ClN₅O₂
Molecular Weight:461.94

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

BTK ligand 3 Chemical Structure

CAS No.: 2192282-58-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BTK ligand 3 is a BTK ligand that can be used for the synthesis of PROTACs, such as PROTAC BTK Degrader-5 (HY-155072)^[1].

Chemical Information

CAS No. 2192282-58-7
Molecular Weight 461.94
Formula C₂₅H₂₄ClN₅O₂
SMILES

N[C@H]1CC[C@H](CC1)NC2=NC=NC3=C2C(C(C4=CC=C(C=C4Cl)OC5=CC=CC=C5)=O)=CN3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Song Chen, et al. Discovery of novel BTK PROTACs with improved metabolic stability via linker rigidification strategy. European Journal of Medicinal Chemistry.Volume 255, 5 July 2023, 115403. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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