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Cat. No.: HY-P1325

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BWX 46

(Synonyms: ((Cys31, Nva 34)-Neuropeptide Y (27-36))2)

BWX 46 (((Cys31, Nva 34)-Neuropeptide Y (27-36))2) is a selective Y₅ receptor agonist with an IC₅₀ value of 0.85 nM. BWX 46 can inhibit the synthesis of cAMP in Y₅ cells.

For research use only. We do not sell to patients.

CAS No.: 172997-92-1
Formula: C₁₁₆H₁₈₆N₃₆O₂₈S₂
Molecular Weight:2597.07

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

BWX 46 Chemical Structure

CAS No.: 172997-92-1

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Sample (0.1mg)

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(In Japan)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

BWX 46 (((Cys31, Nva 34)-Neuropeptide Y (27-36))2) is a selective Y₅ receptor agonist with an IC₅₀ value of 0.85 nM. BWX 46 can inhibit the synthesis of cAMP in Y₅ cells^[1].

IC₅₀ & Target

NPY Y₅ receptor

0.85 nM (IC₅₀)

NPY Y₁ receptor

42 nM ()

NPY Y₂ receptor

3015 nM ()

NPY Y₄ receptor

245 nM ()

All Neuropeptide Y Receptor Isoforms :

Chemical Information

CAS No. 172997-92-1
Molecular Weight 2597.07
Formula C₁₁₆H₁₈₆N₃₆O₂₈S₂
Synonyms

((Cys31, Nva 34)-Neuropeptide Y (27-36))2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Balasubramaniam A, et al. Bis(31/31')[[Cys(31), Nva(34)]NPY(27-36)-NH(2)]: a neuropeptide Y (NPY) Y(5) receptor selective agonist with a latent stimulatory effect on food intake in rats. Peptides. 2002;23(8):1485-1490. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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