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Cat. No.: HY-183579

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c-Met-IN-27

c-Met-IN-27 (Compound T2) is a c-Met kinase inhibitor with a pIC₅₀ of 8.03. c-Met-IN-27 can be used for cancer research.

For research use only. We do not sell to patients.

Formula: C₄₂H₃₅F₇N₄O₄
Molecular Weight:792.74

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

c-Met-IN-27 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

c-Met-IN-27 (Compound T2) is a c-Met kinase inhibitor with a pIC₅₀ of 8.03. c-Met-IN-27 can be used for cancer research^[1].

IC₅₀ & Target^[1]

c-Met

8.03 (pIC₅₀)

Chemical Information

Molecular Weight 792.74
Formula C₄₂H₃₅F₇N₄O₄
SMILES

COC1=C(OCCCN2CCC(C(F)(F)F)CC2)C=C(N=CC=C3OC4=CC=C(NC(C5=CC(C6=CC=CC(C(F)(F)F)=C6)=NC7=C5C=CC=C7)=O)C=C4F)C3=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Boutalaka M, et al. Computational investigation of bisquinoline derivatives as potential c-met kinase inhibitors: 3D-QSAR, molecular docking, dynamics simulations, and ADME-Tox studies. Heliyon. 2026 May 1;12(8).

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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