PD-159020
PD-159020 is a non-selective ETA/ETB antagonist, with IC50s of 30 and 50 nM for hETA and hETB, respectively.
For research use only. We do not sell to patients.
- CAS No.: 177904-00-6
- Formula: C32H25NO8
- Molecular Weight:551.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 30 nM (hETA), 50 nM (hETB)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO-K1 | IC50 |
0.05 μM
Compound: 37
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Inhibitory concentration against Endothelin B receptor expressed in CHO-K1 cells
Inhibitory concentration against Endothelin B receptor expressed in CHO-K1 cells
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10.1016/0960-894X(96)00170-9 |
PD-159020 demonstrates excellent inhibition of arachidonic acid release, AAR-B, with an IC50 of 0.23 μM.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 177904-00-6
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Molecular Weight 551.54
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Formula C32H25NO8
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SMILES
O=C(C(N1CC2=CC=C(OCO3)C3=C2)=C(C4=CC=C(OCO5)C5=C4)C6=C1C=C(OCC7=CC=CC=C7)C(OC)=C6)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PD-159020 Related Classifications
HY-101598 Related Classifications
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