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Cat. No.: HY-N17846

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Dimethyl lithospermate

Dimethyl lithospermate is an antioxidant. Dimethyl lithospermate scavenges DPPH free radicals and inhibits free radical generation. Dimethyl lithospermate also protects hepatocytes from tert-butyl hydroperoxide (t-BHP)-induced oxidative damage. Dimethyl lithospermate can be used in oxidative damage-related research.

For research use only. We do not sell to patients.

CAS No.: 54844-34-7
Formula: C₂₉H₂₆O₁₂
Molecular Weight:566.51

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Dimethyl lithospermate Chemical Structure

CAS No.: 54844-34-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Dimethyl lithospermate (2-50 μM; 30 min) dose-dependently inhibits free radical production in AC₂F hepatocytes^[1].
Dimethyl lithospermate (2-50 μM; 1 h) dose-dependently protects AC₂F hepatocytes against t-BHP-induced injury^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

AC₂F liver cells
Concentration:

2 μM, 10 μM, 50 μM
Incubation Time:

1 h
Result:

Increased viable cell number to 133.49 at 2 μM. (control group viable cell number: 100)
Increased viable cell number to 168.88 at 10 μM.
Increased viable cell number to 171.73 at 50 μM.

Chemical Information

CAS No. 54844-34-7
Molecular Weight 566.51
Formula C₂₉H₂₆O₁₂
SMILES

COC([C@H]1C2=C(/C=C/C(O[C@@H](C(OC)=O)CC3=CC(O)=C(C=C3)O)=O)C=CC(O)=C2O[C@@H]1C4=CC(O)=C(C=C4)O)=O
Structure Classification
- Phenols
- Polyphenols
Initial Source
- Plants
- Labiatae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kang HS, et al. Antioxidant effect ofSalvia miltiorrhiza. Arch Pharm Res. 1997 Oct;20(5):496-500. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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