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Cat. No.: HY-169301

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Gpr35 modulator 1

Gpr35 modulator 1 (compound 1-18) is a potent modulator of Gpr35, with the IC₅₀ of ≤ 100 nM in HEK293 cells stably transfected with human GPR35.

For research use only. We do not sell to patients.

CAS No.: 2994189-01-2
Formula: C₂₃H₁₄ClF₂N₅O₃
Molecular Weight:481.84

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Gpr35 modulator 1 Chemical Structure

CAS No.: 2994189-01-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Gpr35 modulator 1 (compound 1-18) is a potent modulator of Gpr35, with the IC₅₀ of ≤ 100 nM in HEK293 cells stably transfected with human GPR35^[1].

Chemical Information

CAS No. 2994189-01-2
Molecular Weight 481.84
Formula C₂₃H₁₄ClF₂N₅O₃
SMILES

O=C(C1=COC2=CC(C3=NN=NN3)=C(C=C21)F)NC4=CC=C(C=C4)OCC5=CC=C(C=C5Cl)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Crossignal Therapeutics, Inc. Preparation of tetrazoles and related heterocycles as Gpr35 modulators useful in treatment of cancer. World Intellectual Property Organization, WO2023196538 A1 2023-10-12

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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