IR-806
Based on 1 Customer Validation
IR-806 is a near-infrared cyanine liquid crystal dye. IR-806 can be used as a molecular antenna to synthesized nanoprobes (NPs). IR-806 can be used for in vivo imaging studies.
For research use only. We do not sell to patients.
- Purity: 98.84%
- CAS No.: 757960-10-4
- Formula: C37H44ClN2NaO6S2
- Molecular Weight:735.33
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IR-806 (0.1 mg) and folic acid (0.02 mg) were activated with EDC/NHS (1×10−4 mol) in DMSO (10 mL) solution. After 30 mins, the PL-PEG-NH2 coated UCN solution (containing UCNs 5 mg) was added and stirred at room temperature for 4 hrs. The reaction product was purified by centrifugation at 10,000 rpm for 5 mins and suspended in 5 mL of DMSO, obtained upconversion nanocrystals (UCNs) for the preparation of nanoprobes[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 757960-10-4
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Appearance Solid
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Molecular Weight 735.33
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Formula C37H44ClN2NaO6S2
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Color Green to dark green
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SMILES
CC(C)(/C1=C/C=C2C(Cl)=C(CC/2)/C=C/C3=[N+](C4=C(C3(C)C)C=CC=C4)CCCCS(=O)(O[Na])=O)C5=C(C=CC=C5)N1CCCCS(=O)([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (135.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Zhang YF, et al. Multiple hybridized resonances of IR-806 chromonic molecules strongly coupled to Au nanorods. Nanoscale. 2015 May 14;7(18):8503-9. [Content Brief]
[2]. Wei Y, et al. Molecular Antenna-Sensitized Upconversion Nanoparticle for Temperature Monitored Precision Photothermal Therapy. Int J Nanomedicine. 2020 Mar 2;15:1409-1420. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3599 mL | 6.7997 mL | 13.5993 mL | 33.9983 mL |
| 5 mM | 0.2720 mL | 1.3599 mL | 2.7199 mL | 6.7997 mL | |
| 10 mM | 0.1360 mL | 0.6800 mL | 1.3599 mL | 3.3998 mL | |
| 15 mM | 0.0907 mL | 0.4533 mL | 0.9066 mL | 2.2666 mL | |
| 20 mM | 0.0680 mL | 0.3400 mL | 0.6800 mL | 1.6999 mL | |
| 25 mM | 0.0544 mL | 0.2720 mL | 0.5440 mL | 1.3599 mL | |
| 30 mM | 0.0453 mL | 0.2267 mL | 0.4533 mL | 1.1333 mL | |
| 40 mM | 0.0340 mL | 0.1700 mL | 0.3400 mL | 0.8500 mL | |
| 50 mM | 0.0272 mL | 0.1360 mL | 0.2720 mL | 0.6800 mL | |
| 60 mM | 0.0227 mL | 0.1133 mL | 0.2267 mL | 0.5666 mL | |
| 80 mM | 0.0170 mL | 0.0850 mL | 0.1700 mL | 0.4250 mL | |
| 100 mM | 0.0136 mL | 0.0680 mL | 0.1360 mL | 0.3400 mL |
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