JMV 170
JMV 170, a CCK derivative, is a selective CCK-B agonist. JMV 170 binds to the CCK-B receptor with a 10-fold higher affinity than to the CCK-A receptor. JMV 170 shows contractile effects on pig smooth muscle cells with an EC50 of 9 pmol/L.
For research use only. We do not sell to patients.
- CAS No.: 117829-60-4
- Formula: C51H68N8O14S
- Molecular Weight:1049.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 117829-60-4
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Molecular Weight 1049.21
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Formula C51H68N8O14S
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SMILES
C([C@@H](C(N[C@H](C(N[C@H](C(NCCC1=CC=CC=C1)=O)CC(O)=O)=O)CCCC)=O)NC(CNC([C@@H](NC([C@H](CC2=CC=C(OS(=O)(=O)O)C=C2)NC(OC(C)(C)C)=O)=O)CCCC)=O)=O)C=3C=4C(NC3)=CC=CC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Gue M, et al. Neuropeptide Y and sigma ligand (JO 1784) suppress stress-induced colonic motor disturbances in rats through sigma and cholecystokinin receptors. J Pharmacol Exp Ther. 1992 Jun;261(3):850-5. [Content Brief]
[2]. Botella A, et al. Cholecystokinin and gastrin induce cell contraction in pig ileum by interacting with different receptor subtypes. Gastroenterology. 1992 Mar;102(3):779-86. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JMV 170 Related Classifications
HY-P1994A Related Classifications
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