4-Methoxycinnamic acid
Based on 1 Customer Validation
4-Methoxycinnamic acid is detected as natural phenylpropanoid in A. preissii.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.87%
- CAS No.: 830-09-1
- Formule: C10H10O3
- Masse moléculaire:178.19
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
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Human Endogenous Metabolite |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>100 μM
Compound: PMOCA
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Antiproliferative activity against human HepG2 cells incubated for 72 hrs by CCK8 cells
Antiproliferative activity against human HepG2 cells incubated for 72 hrs by CCK8 cells
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[PMID: 31200238] |
| HepG2 | IC50 |
8.56 μM
Compound: PMOCA
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Antiproliferative activity against human HepG2 cells incubated for 72 hrs in presence of oridonin by CCK8 cells
Antiproliferative activity against human HepG2 cells incubated for 72 hrs in presence of oridonin by CCK8 cells
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[PMID: 31200238] |
| PLC-PRF-5 | IC50 |
>100 μM
Compound: PMOCA
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Antiproliferative activity against human PLC/PRF/5 cells incubated for 72 hrs by CCK8 cells
Antiproliferative activity against human PLC/PRF/5 cells incubated for 72 hrs by CCK8 cells
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[PMID: 31200238] |
| PLC-PRF-5 | IC50 |
6.55 μM
Compound: PMOCA
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Antiproliferative activity against human PLC/PRF/5 cells incubated for 72 hrs in presence of oridonin by CCK8 cells
Antiproliferative activity against human PLC/PRF/5 cells incubated for 72 hrs in presence of oridonin by CCK8 cells
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[PMID: 31200238] |
4-Methoxycinnamic acid is an unusual phenylpropanoid involved in phenylphenalenone biosynthesis in Anigozanthos preissii[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 830-09-1
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Appearance Solid
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Masse moléculaire 178.19
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Formule C10H10O3
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Color Off-white to light yellow
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SMILES
O=C(O)/C=C/C1=CC=C(OC)C=C1
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvant et solubilité
DMSO : 50 mg/mL (280.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (14.03 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (14.03 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureté et documentation
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Fiche technique (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.6121 mL | 28.0604 mL | 56.1208 mL | 140.3020 mL |
| 5 mM | 1.1224 mL | 5.6121 mL | 11.2242 mL | 28.0604 mL | |
| 10 mM | 0.5612 mL | 2.8060 mL | 5.6121 mL | 14.0302 mL | |
| 15 mM | 0.3741 mL | 1.8707 mL | 3.7414 mL | 9.3535 mL | |
| 20 mM | 0.2806 mL | 1.4030 mL | 2.8060 mL | 7.0151 mL | |
| 25 mM | 0.2245 mL | 1.1224 mL | 2.2448 mL | 5.6121 mL | |
| 30 mM | 0.1871 mL | 0.9353 mL | 1.8707 mL | 4.6767 mL | |
| 40 mM | 0.1403 mL | 0.7015 mL | 1.4030 mL | 3.5076 mL | |
| 50 mM | 0.1122 mL | 0.5612 mL | 1.1224 mL | 2.8060 mL | |
| 60 mM | 0.0935 mL | 0.4677 mL | 0.9353 mL | 2.3384 mL | |
| 80 mM | 0.0702 mL | 0.3508 mL | 0.7015 mL | 1.7538 mL | |
| 100 mM | 0.0561 mL | 0.2806 mL | 0.5612 mL | 1.4030 mL |
4-Methoxycinnamic acid Related Classifications
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