Anticancer agent 254
Based on 1 Customer Validation
Anticancer agent 254 (compound 10) is a dichloroacetic acid-loaded compound with enhanced antitumor activity against leukemia cells in vitro and better stability in vivo, and can be considered for preclinical evaluation of cancer inhibition.
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- Pureté : 95.62%
- CAS No.: 1841421-67-7
- Formule: C12H18Cl6N4O3
- Masse moléculaire:479.01
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
0.34 mM
Compound: 10
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Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
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[PMID: 26653539] |
| JVM-2 | IC50 |
0.41 mM
Compound: 10
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Cytotoxicity against human JVM2 cells after 48 hrs by MTT assay
Cytotoxicity against human JVM2 cells after 48 hrs by MTT assay
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[PMID: 26653539] |
| Maver1 | IC50 |
0.55 mM
Compound: 10
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Cytotoxicity against human Maver1 cells after 48 hrs by MTT assay
Cytotoxicity against human Maver1 cells after 48 hrs by MTT assay
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[PMID: 26653539] |
| PBMC | IC50 |
1.26 mM
Compound: 10
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Cytotoxicity against human PBMC cells after 48 hrs by MTT assay
Cytotoxicity against human PBMC cells after 48 hrs by MTT assay
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[PMID: 26653539] |
Chemical Information
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CAS No. 1841421-67-7
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Appearance Solid
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Masse moléculaire 479.01
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Formule C12H18Cl6N4O3
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Color White to off-white
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SMILES
ClC(C(NCCN(CCNC(C(Cl)Cl)=O)CCNC(C(Cl)Cl)=O)=O)Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
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Fiche technique (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 254 Related Classifications
HY-119324 Related Classifications
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