ASP3026 (Standard)
ASP3026 (Standard) is the analytical standard of ASP3026. This product is intended for research and analytical applications. ASP3026 is a selective and orally active inhibitor of anaplastic lymphoma kinase (ALK). ASP3026 is a selective and oral active anaplastic lymphoma kinase (ALK) inhibitor with a IC50 value of 3.5 nM. ASP3026 can inhibit the phosphorylation of IGF-1R, STAT3, AKT and JNK proteins, and induce the cleavage of caspase 3 and PARP. It also inhibited ROS and ACK. ASP3026 can be used in anti-tumor research.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 98%
- CAS No.: 1097917-15-1
- Formule: C29H40N8O3S
- Masse moléculaire:580.74
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1097917-15-1
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Masse moléculaire 580.74
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Formule C29H40N8O3S
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SMILES
COC(C=C(N1CCC(N2CCN(C)CC2)CC1)C=C3)=C3NC4=NC=NC(NC5=C(S(C(C)C)(=O)=O)C=CC=C5)=N4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- ASP3026 (Standard)
- 1097917-15-1
- Anaplastic lymphoma kinase (ALK)
- Apoptosis
- ROS Kinase
- Caspase
- PARP
- IGF-1R
- STAT
- Akt
- JNK
- Anaplastic lymphoma kinase
- ALK tyrosine kinase receptor
- CD246
- Cluster of differentiation 246
- poly ADP ribose polymerase
- Insulin-like growth factor-1 receptor
- PKB
- Protein kinase B
- c-Jun N-terminal kinase
- apoptosis
- anticancer
- NCI-H2228 cell
- non-small cell lung cancer (NSCLC)
- NPM-ALK+ T-cell
- anaplastic large-cell lymphoma (ALCL)
- proliferation
- cell viability
- Inhibitor
- inhibitor
- inhibit