BAY 1892005
Based on 1 Customer Validation
BAY 1892005 is a regulator of p53 protein and acts on p53 condensates without causing mutant p53 reactivation.
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- Pureté: 99.44%
- CAS No.: 2036352-13-1
- Formule: C11H8ClFN2OS
- Masse moléculaire:270.71
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
BAY 1892005 inhibits cell proliferation in p53 mutated cell lines Huh7 (IC50=11.2 μM) and H358 (IC50=11.1 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2036352-13-1
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Appearance Solid
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Masse moléculaire 270.71
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Formule C11H8ClFN2OS
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Color Off-white to light yellow
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SMILES
O=C(NC1=NC(C2=CC=CC=C2F)=CS1)CCl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 250 mg/mL (923.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6940 mL | 18.4699 mL | 36.9399 mL | 92.3497 mL |
| 5 mM | 0.7388 mL | 3.6940 mL | 7.3880 mL | 18.4699 mL | |
| 10 mM | 0.3694 mL | 1.8470 mL | 3.6940 mL | 9.2350 mL | |
| 15 mM | 0.2463 mL | 1.2313 mL | 2.4627 mL | 6.1566 mL | |
| 20 mM | 0.1847 mL | 0.9235 mL | 1.8470 mL | 4.6175 mL | |
| 25 mM | 0.1478 mL | 0.7388 mL | 1.4776 mL | 3.6940 mL | |
| 30 mM | 0.1231 mL | 0.6157 mL | 1.2313 mL | 3.0783 mL | |
| 40 mM | 0.0923 mL | 0.4617 mL | 0.9235 mL | 2.3087 mL | |
| 50 mM | 0.0739 mL | 0.3694 mL | 0.7388 mL | 1.8470 mL | |
| 60 mM | 0.0616 mL | 0.3078 mL | 0.6157 mL | 1.5392 mL | |
| 80 mM | 0.0462 mL | 0.2309 mL | 0.4617 mL | 1.1544 mL | |
| 100 mM | 0.0369 mL | 0.1847 mL | 0.3694 mL | 0.9235 mL |
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