BCX 1470
BCX 1470 inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.
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- CAS No.: 217099-43-9
- Formule: C14H10N2O2S2
- Masse moléculaire:302.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
IC50: 96 nM (Factor D); 1.6 nM (C1s); 326 nM (Trypsin)
BCX 1470 is serine protease inhibitor. BCX 1470 blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro, also blocked development of RPA-induced edema in the rat.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 217099-43-9
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Masse moléculaire 302.37
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Formule C14H10N2O2S2
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SMILES
N=C(C1=CC2=CC=C(OC(C3=CC=CS3)=O)C=C2S1)N
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)