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Cat. No.: HY-161085

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BI 1265162

BI 1265162 is a potent inhibitor of endothelial sodium channel (ENaC) that plays an important role in cystic fibrosis research.

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CAS No.: 3042822-44-3
Formule: C₂₄H₃₆ClN₇O₉P₂
Masse moléculaire:663.98

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

BI 1265162 Chemical Structure

CAS No.: 3042822-44-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Essai clinique
Chemical Information
Pureté et documentation
Références
Calculators
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Classifications
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Activité biologique

Description

BI 1265162 is a potent inhibitor of endothelial sodium channel (ENaC) that plays an important role in cystic fibrosis research^[1].

Voir tous les produits spécifiques à Isoform Sodium Channel :

Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 3042822-44-3
Masse moléculaire 663.98
Formule C₂₄H₃₆ClN₇O₉P₂
SMILES

ClC1=CN=C(N)C(C(NCC2=[N+](CC)C(C=CC(OCC(NCCOCP(C)(C)=O)=O)=C3)=C3N2CC)=O)=N1.[O-]P(O)(O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Bodo Betzemeier, et al. Discovery and development of BI 1265162, an ENaC inhibitor for the treatment of cystic fibrosis. European Journal of Medicinal Chemistry, 2023, 116038, ISSN 0223-5234,

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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BI 1265162

Voir tous les produits spécifiques à Isoform Sodium Channel

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

BI 1265162 Related Classifications

HY-161085 Related Classifications