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Cat. No.: HY-125748

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CBM-301940

Name: CBM-301940
Brand: MedChemExpress
SKU: HY-125748
Price: 410.00 USD
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1 Cited Publications

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CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC₅₀ value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases.

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Pureté : 99.4%
CAS No.: 902146-11-6
Formule: C₁₅H₂₀F₆N₂O₅
Masse moléculaire:422.32

Stockage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

CBM-301940 Chemical Structure

CAS No.: 902146-11-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Publications (1)
Pureté et documentation
Références
Calculators
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Activité biologique

Description

CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC₅₀ value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases^[1].

IC₅₀ & Target

Malonate CoA Decarboxylase (MCD)^[1]

Chemical Information

CAS No. 902146-11-6
Appearance Solid
Masse moléculaire 422.32
Formule C₁₅H₂₀F₆N₂O₅
Color White to light yellow
SMILES

CC(NC(C1=NOC(C(C(F)(F)F)(O)C(F)(F)F)C1)=O)CC(OC(C)(C)C)=O
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Publications (1)

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Cancer Res

FASN Inhibition Enhances the Efficacy of Chemotherapy in Colorectal Cancer by Inhibiting the DNA Damage Response. [Abstract]

2026 Feb 9. PMID: 41661672

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Cheng JF, et al. Discovery of potent and orally available malonyl-CoA decarboxylase inhibitors as cardioprotective agents. J Med Chem. 2006 Jul 13;49(14):4055-8. doi: 10.1021/jm0605029. PMID: 16821767. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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CBM-301940

1 Cited Publications

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Publications (1)
Pureté et documentation
Références

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CBM-301940

Publications Citing Use of MedChemExpress (MCE) CBM-301940