Cliramitug
Based on 1 Customer Validation
Cliramitug (NI-006; ALXN2220) is a monoclonal antibody that targets human transthyretin (TTR). Cliramitug binds to TTR and inhibits its amyloidogenic process, exerting amyloid formation-inhibiting activity. Cliramitug can be used in the research of transthyretin amyloidosis-related diseases, such as certain neurological and cardiovascular diseases.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 97.0%
- CAS No.: 2965214-50-8
- Masse moléculaire:144.542 kDa
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Human IgG1 kappa
Human
Transthyretin/TTR
Cliramitug accelerates phagocyte-mediated clearance of dense-structured ATTR amyloid fibrils in vitro[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG1-kappa
ELISA, FACS, Functional assay
Chemical Information
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CAS No. 2965214-50-8
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Appearance Liquid
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Masse moléculaire 144.542 kDa
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Color Colorless to light yellow
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SMILES
[Cliramitug]
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Synonyms
NI-006; ALXN2220
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Livraison
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
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Fiche technique (255 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cliramitug Related Classifications
Cat. No.: HY-P991128
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- Cliramitug
- 2965214-50-8
- NI-006
- ALXN2220
- NI006
- NI 006
- ALXN2220
- ALXN 2220
- ALXN-2220
- Transthyretin (TTR)
- TTR monomers
- macrophage-mediated phagocytosis
- TTR amyloid fibrils
- transthyretin cardiac amyloidosis
- patient-derived fibril xenograft mice
- phagocyte-mediated clearance
- ATTR amyloid fibrils
- conformationally exposed peptide epitope
- cardiac amyloid deposits
- TTR tetramers
- Inhibitor
- inhibitor
- inhibit