Coronarin D
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Coronarin D is a cytotoxic labdan-type diterpenes compound isolated from the rhizomes of H. coronarium.
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- Pureté: 97.0%
- CAS No.: 119188-37-3
- Formule: C20H30O3
- Masse moléculaire:318.45
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI50 |
8 μM
Compound: 3
|
Growth inhibition of human A549 cells by Sulforhodamine B assay
Growth inhibition of human A549 cells by Sulforhodamine B assay
|
[PMID: 21106458] |
| BMDC | IC50 |
41.72 μM
Compound: 4
|
Antiinflammatory activity in C57BL/6 mouse BMDC assessed as inhibition of LPS-stimulated TNF-alpha production preincubated for 1 hr before LPS-stimulation measured after 16 hrs by ELISA
Antiinflammatory activity in C57BL/6 mouse BMDC assessed as inhibition of LPS-stimulated TNF-alpha production preincubated for 1 hr before LPS-stimulation measured after 16 hrs by ELISA
|
[PMID: 22071304] |
| HeLa | GI50 |
47 μM
Compound: 3
|
Growth inhibition of human HeLa cells by Sulforhodamine B assay
Growth inhibition of human HeLa cells by Sulforhodamine B assay
|
[PMID: 21106458] |
| MCF7 | GI50 |
17.4 μM
Compound: 3
|
Growth inhibition of human MCF7 cells by Sulforhodamine B assay
Growth inhibition of human MCF7 cells by Sulforhodamine B assay
|
[PMID: 21106458] |
| SK-N-SH | GI50 |
20.1 μM
Compound: 3
|
Growth inhibition of human SK-N-SH cells by Sulforhodamine B assay
Growth inhibition of human SK-N-SH cells by Sulforhodamine B assay
|
[PMID: 21106458] |
Chemical Information
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CAS No. 119188-37-3
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Appearance Solid
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Masse moléculaire 318.45
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Formule C20H30O3
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Color White to off-white
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SMILES
CC1(C2C/C=C3C(OC(O)C\3)=O)C(CCC2=C)C(C)(CCC1)C
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Pureté et documentation
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Fiche technique (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)