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CP-100356

9 Cited Publications
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Based on 9 publication(s) in Google Scholar

CP-100356 is an orally active dual MDR1 (P-gp)/BCRP inhibitor, with an IC50s of 0.5 and 1.5 µM for inhibiting MDR1-mediated Calcein-AM transport and BCRP-mediated Prazosin transport, respectively. CP-100356 is also a weak inhibitor of OATP1B1 (IC50 = ∼66 µM). CP-100356 is devoid of inhibition against MRP2 and major human P450 enzymes (IC50 > 15 µM).

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  • CAS No.: 142716-85-6
  • Formule: C31H36N4O6
  • Masse moléculaire:560.64
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • CP-100356 Chemical Structure
    CP-100356 Chemical Structure
CAS No.: 142716-85-6
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[email protected] [email protected]
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