CP 81282
CP 81282 is a tripeptide aspartic protease inhibitor, with an IC50 of 1 nM against human renin and an IC50 of 11 nM against endopeptidase. CP 81282 is applicable to the research of hypertension.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 121584-61-0
- Formule: C32H47F2N5O6
- Masse moléculaire:635.74
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
CP 81282 potently inhibits human plasma renin with an IC50 of 1 nM and endothiapepsin with an IC50 of 11 nM[1].
CP 81282 binds to endothiapepsin as a tetrahedral hydrate, forming specific hydrogen bonds with active-site aspartates 32 and 215, and adopts an extended conformation that interacts with additional enzyme residues[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 121584-61-0
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Masse moléculaire 635.74
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Formule C32H47F2N5O6
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SMILES
CNC(C(F)(C(C(NC(C(NC(C(CC1=CC=CC=C1)NC(N2CCOCC2)=O)=O)CCCC)=O)CC3CCCCC3)=O)F)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CP 81282 Related Classifications
HY-117641 Related Classifications
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