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Cat. No.: HY-118120

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GEMSA

Name: GEMSA
Brand: MedChemExpress
SKU: HY-118120
Price: 485.00 USD
Availability: PreOrder

(Synonyms: 2-Guanidinoethylmercaptosuccinic acid)

GEMSA is a potent inhibitor of enkephalin convertase (K_i=8.8 nM). GEMSA elicites analgesia.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Pureté: 98%
CAS No.: 77482-44-1
Formule: C₇H₁₃N₃O₄S
Masse moléculaire:235.26

Stockage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

GEMSA Chemical Structure

CAS No.: 77482-44-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
Pureté et documentation
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Calculators
Help & FAQs
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Activité biologique

Description

GEMSA is a potent inhibitor of enkephalin convertase (K_i=8.8 nM). GEMSA elicites analgesia^[1].

IC₅₀ & Target

Encephalin convertase, K_i 值为8.8 nM.

In Vitro

GEMSA inhibits the activation of TAFI and porcine CBB^[1].
GEMSA can inhibit the prolongation of lysis time in recombinant BAP and does not lead to the lysis of APC fibronectin^[1].
GEMSA inhibits the prolongation of lysis time in porcine CPB, TAFI, and recombinant BAP, APC with the EC₅₀ values of 0.34 μM, 100μM, 115 μM, 90 μM respectively^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

GEMSA (ICV, 0.1μg/mg, every, 3days) results in a 75% increase in hypothalamic luteinizing hormone-releasing hormone and serum luteinizing hormone levels, and a 60% decrease in serum prolactin concentrations in rat^[3]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 77482-44-1
Appearance Solid
Masse moléculaire 235.26
Formule C₇H₁₃N₃O₄S
Color White to off-white
SMILES

OC(C(SCCNC(N)=N)CC(O)=O)=O
Synonyms

2-Guanidinoethylmercaptosuccinic acid
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. B Przewlocka, et al. Analgesic and convulsant effects of guanidinoethylmercaptosuccinic acid (GEMSA)--a potent enkephalin convertase inhibitor. Neuropeptides. Nov-Dec 1986;8(4):359-65. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
Pureté et documentation
Références

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GEMSA

2-PMPA

2-MPPA

2-PMPA (Standard)

2-MPPA (Standard)

ZJ43

Mergetpa

2-Benzylsuccinic acid

CPA inhibitor

Carboxypeptidase G2 (CPG2) Inhibitor

GCPII-IN-1 TFA

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Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Bioz

GEMSA

2-PMPA

2-MPPA

2-PMPA (Standard)

2-MPPA (Standard)

ZJ43

Mergetpa

2-Benzylsuccinic acid

CPA inhibitor

Carboxypeptidase G2 (CPG2) Inhibitor

GCPII-IN-1 TFA

2-Benzylsuccinic acid (Standard)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

GEMSA Related Classifications

HY-118120 Related Classifications

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