SYNRG - synergin gamma Gene

Also Known as SYNG; AP1GBP1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 11276

About SYNRG

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:37,514,807-37,609,418 (from NCBI)

This gene has 16 transcripts (splice variants), 1 gene allele and 206 orthologues. Ubiquitous expression in lymph node (RPKM 8.0), spleen (RPKM 6.7) and 25 other tissues.

Summary

This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to Other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

SYNRG Products (8)

mRNA Protein Name
NM_001163544.3 NP_001157016.1 synergin gamma isoform 4
NM_001163545.3 NP_001157017.1 synergin gamma isoform 5
NM_001163546.3 NP_001157018.1 synergin gamma isoform 6
NM_001163547.3 NP_001157019.1 synergin gamma isoform 7
NM_001405103.1 NP_001392032.1 synergin gamma isoform 8
NM_007247.6 NP_009178.3 synergin gamma isoform 1
NM_080550.5 NP_542117.3 synergin gamma isoform 2
NM_198882.3 NP_942583.1 synergin gamma isoform 3
Protein Preferred Names Protein Names

synergin gamma

  • AP1 gamma subunit binding protein 1

SYNRG Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
SYNRG Q9UMZ2 APPBP2 Homo sapiens Q92624
Validated Y2H
25416956
Intra
SYNRG Q9UMZ2 APPBP2 Homo sapiens Q92624
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Chromosome 17q12 Deletion Syndrome

  • 17q12 Microdeletion Syndrome

  • Del(17)(Q12)

  • Monosomy 17q12
Mixed Phenotype Acute Leukemia, B/Myeloid

  • Doid:0081038
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS14101 SYNRG Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SYNRG RGD RGD:620684
Bos taurus SYNRG VGNC VGNC:35533
Mus musculus SYNRG MGD MGI:1354742
Canis familiaris SYNRG VGNC VGNC:47038
Felis catus SYNRG VGNC VGNC:67722
Macaca mulatta SYNRG VGNC VGNC:78262
Others SYNRG NCBI