2. Gene
  3. SYNRG - synergin gamma Gene

SYNRG - synergin gamma Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SYNG; AP1GBP1

Gene ID: 11276 | Gene type: protein coding

About SYNRG

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:37,514,807-37,609,418 (from NCBI)

This gene has 16 transcripts (splice variants), 1 gene allele and 206 orthologues. Ubiquitous expression in lymph node (RPKM 8.0), spleen (RPKM 6.7) and 25 other tissues.

Summary

This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

SYNRG Products(8)

mRNA Protein Name
NM_001163544.3 NP_001157016.1 synergin gamma isoform 4
NM_001163545.3 NP_001157017.1 synergin gamma isoform 5
NM_001163546.3 NP_001157018.1 synergin gamma isoform 6
NM_001163547.3 NP_001157019.1 synergin gamma isoform 7
NM_001405103.1 NP_001392032.1 synergin gamma isoform 8
NM_007247.6 NP_009178.3 synergin gamma isoform 1
NM_080550.5 NP_542117.3 synergin gamma isoform 2
NM_198882.3 NP_942583.1 synergin gamma isoform 3
Protein Preferred Names Protein Names

synergin gamma

AP1 gamma subunit binding protein 1

Related Diseases

Diseases Alias
Chromosome 17q12 Deletion Syndrome

17q12 Microdeletion Syndrome

Del(17)(Q12)

Monosomy 17q12
Mixed Phenotype Acute Leukemia, B/Myeloid

Doid:0081038
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14101 SYNRG Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SYNRG RGD RGD:620684
Bos taurus SYNRG VGNC VGNC:35533
Mus musculus SYNRG MGD MGI:1354742
Canis familiaris SYNRG VGNC VGNC:47038
Felis catus SYNRG VGNC VGNC:67722
Macaca mulatta SYNRG VGNC VGNC:78262