ARGLU1 - arginine and glutamate rich 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55082

About ARGLU1

Cytogenetic location: 13q33.3 Genomic coordinates (GRCh38): 13:106,541,673-106,568,137 (from NCBI)

This gene has 4 transcripts (splice variants) and 210 orthologues. Ubiquitous expression in lung (RPKM 83.2), spleen (RPKM 81.9) and 25 other tissues.

Summary

Enables Cadherin binding activity. Located in cytosol; mitochondrion; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ARGLU1 Products (1)

mRNA Protein Name
NM_018011.4 NP_060481.3 arginine and glutamate-rich protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables nuclear receptor coactivator activity IMP
IMP: Inferred from mutant phenotype
30698747 GOA
enables pre-mRNA binding IDA
IDA: Inferred from direct assay
30698747 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
22365833 GOA
Biological Process GO Annotation Evidence Références Source
involved in regulation of alternative mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
30698747 GOA
Cellular Component GO Annotation Evidence Références Source
located in nuclear speck IDA
IDA: Inferred from direct assay
30698747 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ARGLU1 Protein Structure

ARGLU

ARGLU: Arginine and glutamate-rich 1 (119 - 269)

  • 0
  • 100
  • 200
  • 273 a.a.
Protein Preferred Names Protein Names

arginine and glutamate-rich protein 1

ARGLU1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
ARGLU1 Q9NWB6 PUF60 Homo sapiens Q9UHX1
Anti Tag CoIP
30698747
Intra
ARGLU1 Q9NWB6 PUF60 Homo sapiens Q9UHX1
Confocal
30698747
Intra
ARGLU1 Q9NWB6 SRPK2 Homo sapiens P78362
Protein Kinase Assay
23602568
Intra
ARGLU1 Q9NWB6 JMJD6 Homo sapiens Q6NYC1
Anti Tag CoIP
30698747
Intra
ARGLU1 Q9NWB6 JMJD6 Homo sapiens Q6NYC1
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Conventional Angiosarcoma
Brain Small Vessel Disease 2

  • Porencephaly 2

  • BSVD2

  • Gould Syndrome 2

  • Porencephaly 2, Formerly

  • Poren2, Formerly

  • Poren2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS00910 ARGLU1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ARGLU1 MGD MGI:2442985
Bos taurus ARGLU1 VGNC VGNC:26072
Rattus norvegicus ARGLU1 RGD RGD:1310061
Macaca mulatta ARGLU1 VGNC VGNC:106250
Felis catus ARGLU1 VGNC VGNC:59873
Canis familiaris ARGLU1 VGNC VGNC:38043
Others ARGLU1 NCBI