Gluconapin
Gluconapin (3-Butenyl glucosinolate) is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin inhibits the elevation of plasma triglyceride levels in mice. Gluconapin also exhibits certain antibacterial activity.
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- CAS No.: 19041-09-9
- Formule: C11H19NO9S2
- Masse moléculaire:373.40
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
Gluconapin (4 mM) exhibits weak inhibitory activity against porcine pancreatic lipase, inhibiting only 5.7% of the enzyme activity[2].
Gluconapin (0.15-3.0 μL/mL; 18 h) dose-dependently inhibits the growth of Xanthomonas campestris pv. campestris race 4 strain HRI1279A in vitro[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Slc:ddY mice (6-week-old, male)[2]
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Dosage:40 μmol/kg (14.9 mg/kg); 80 μmol/kg (29.8 mg/kg)
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Administration:p.o.; single dose (immediately before corn oil loading)
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Result:Showed a non-statistically significant tendency to decrease plasma triglyceride levels at 4-8 hours after administration (40 μmol/kg).
Significantly suppressed the elevation of plasma triglyceride levels at 3-8 hours after administration, and reduced the 8-hour area under the plasma triglyceride concentration curve (AUC) to 61.5 ± 6.8% of the control value (p < 0.05 vs.control) (80 μmol/kg).
Chemical Information
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CAS No. 19041-09-9
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Masse moléculaire 373.40
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Formule C11H19NO9S2
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SMILES
O=S(O/N=C(CCC=C)\S[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)(O)=O
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Synonyms
3-Butenyl glucosinolate
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Padilla G, et al. Variation of glucosinolates in vegetable crops of Brassica rapa. Phytochemistry. 2007;68(4):536-545. [Content Brief]
[3]. Velasco P, et al. In vivo and in vitro effects of secondary metabolites against Xanthomonas campestris pv. campestris. Molecules. 2013;18(9):11131-11143. Published 2013 Sep 11. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Gluconapin Related Classifications
HY-N10346A Related Classifications
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