Gossypolone
Based on 1 Customer Validation
Gossypolone is an RNA-binding protein Musashi-1 inhibitor with a Ki of 12 nM. Gossypolone disrupts the Musashi-numb RNA interaction and directly binds to the RBD1 of MSI1 protein. Gossypolone can be used for the research of cancer.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 96.28%
- CAS No.: 4547-72-2
- Formule: C30H26O10
- Masse moléculaire:546.52
-
Stockage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Voir tous les produits spécifiques à Isoform DNA/RNA Synthesis
More
Activité biologique
Musashi-1[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
23.3 μM
Compound: 13, gossypolone
|
Anticancer activity against human HeLa cells after 48 hrs by MTT assay
Anticancer activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 19447525] |
| U-87MG ATCC | IC50 |
26.1 μM
Compound: 13, gossypolone
|
Anticancer activity against human U87 cells after 48 hrs by MTT assay
Anticancer activity against human U87 cells after 48 hrs by MTT assay
|
[PMID: 19447525] |
Chemical Information
-
CAS No. 4547-72-2
-
Appearance Solid
-
Masse moléculaire 546.52
-
Formule C30H26O10
-
Color Light yellow to brown
-
SMILES
O=CC1=C(C(O)=C(C2=C1C(C(C(C3=O)=C(C(C4=C3C(C=O)=C(C(O)=C4C(C)C)O)=O)C)=C(C2=O)C)=O)C(C)C)O
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Pureté et documentation
-
Fiche technique (271 KB)
-
SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
-
Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)